ECHA Opens Public Consultation on Harmonized Classification and Labelling (CLH) Proposals for 4 Substances

Dec 1, 2025

CLH

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In November 2025, the European Chemicals Agency (ECHA) solicited public opinions on the proposal for a unified classification and labeling (CLH) of four substances, with a consultation period of 60 days.

Name	EC Number	CAS Number	Hazard classes open for commenting	Start of consultation	Deadline for commenting
3,5,5-trimethylhexanoic acid and its salts, with the exception of those specified elsewhere in this Annex	-	-	Acute toxicity – oral Reproductive toxicity	17/11/2025	16/01/2026
quizalofop-P-ethyl (ISO); ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	-	100646-51-3	Explosives Flammable solids Self-reactive substances and mixtures Pyrophoric solids Self-heating substances or mixtures Substances or mixtures which in contact with water emit flammable gases Oxidising solids Corrosive to metals Acute toxicity – inhalation Acute toxicity – dermal Acute Toxicity - oral Skin corrosion/irritation Serious eye damage/eye irritation Respiratory sensitisation Skin sensitisation Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity — single exposure Specific target organ toxicity — repeated exposure Aspiration hazard Hazardous to the aquatic environment Hazardous for the ozone layer	17/11/2025	16/01/2026
sodium fluoride	231-667-8	7681-49-4	Acute toxicity – inhalation Acute toxicity – dermal Acute Toxicity - oral Reproductive toxicity Endocrine disruptor for human health	17/11/2025	16/01/2026
2,4,6-tris(dimethylaminomethyl)phenol	202-013-9	90-72-2	Acute toxicity - oral Skin corrosion/irritation Serious eye damage/eye irritation Skin sensitisation	10/11/2025	09/01/2026

The CLH process aims to ensure consistency and transparency in hazard information for chemicals across Europe. This procedure involves assessing the hazardous properties of chemical substances, proposing appropriate classifications and labels, collecting public input, and concluding with a final review and recommendations by ECHA's Committee for Risk Assessment (RAC).

Further Information

ECHA

Related Inventories

EC Inventory: EINECS/ELINCS/NLP

EU REACH Substances of Very High Concern (SVHC) List

EU REACH Restricted Substances List (Annex XVII)

EU List of Approved Biocidal Active Substances (BPR)

EU List of CMR Substances

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