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U.S. EPA Announces Addition of PFHxS-Na to the Toxic Release Inventory (TRI)

Oct 14, 2025
USA
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On October 7, 2025, the U.S. Environmental Protection Agency (EPA) announced that, under the automatic listing mechanism of the National Defense Authorization Act for Fiscal Year 2020 (NDAA), sodium perfluorohexanesulfonate (PFHxS-Na, CAS RN 82382-12-5) has been formally added to the Toxic Release Inventory (TRI). The listing will take effect on January 1, 2026. With this addition, the total number of PFAS subject to TRI reporting has increased to 206.

Background

PFHxS-Na is a common surfactant used in processes such as firefighting foam, metal plating, and semiconductor cleaning. It is persistent, bioaccumulative, and potentially hepatotoxic. In 2025, the EPA released the IRIS Toxicological Review: Perfluorohexanesulfonic Acid (PFHxS, CAS RN 335-46-4) and Related Salts, which for the first time established toxicity values for PFHxS-Na. Although the TRI list previously included PFHxS and other associated salts, PFHxS-Na was not covered.

Recently Added PFAS

CASRN

TRI Chemical Name

Effective Reporting Year

Triggering Activity

307-24-4

Perfluorohexanoic acid

2024

Final Toxicity Value

422-64-0

Perfluoropropanoic acid

2024

Final Toxicity Value

2923-26-4

Sodium perfluorohexanoate

2024

Final Toxicity Value

21615-47-4

Ammonium perfluorohexanoate

2024

Final Toxicity Value

82113-65-3

1,1,1-Trifluoro-N-[(trifluoromethyl)sulfonyl] methanesulfonamide

2024

Final Toxicity Value

90076-65-6

Lithium bis[(trifluoromethyl)sulfonyl] azanide

2024

Final Toxicity Value

2816091-53-7

Betaines, dimethyl(γ-ω-perfluoro-γ-hydro-C8-18-alkyl)

2024

CBI Declassification

377-73-1

Perfluoro-3-methoxypropanoic acid

2025

Final Toxicity Value

3108-42-7

Ammonium perfluorodecanoate (PFDA NH4)

2025

Final Toxicity Value

3830-45-3

Sodium perfluorodecanoate (PFDA-Na)

2025

Final Toxicity Value

27619-97-2 

6:2 Fluorotelomer sulfonate acid 

2025

Final Toxicity Value

425670-75-3 

6:2 Fluorotelomer sulfonate anion 

2025

Final Toxicity Value

59587-38-1 

6:2 Fluorotelomer sulfonate potassium salt 

2025

Final Toxicity Value

59587-39-2

6:2 Fluorotelomer sulfonate ammonium salt

2025

Final Toxicity Value

27619-94-9 

6:2 Fluorotelomer sulfonate sodium salt 

2025

Final Toxicity Value

3030471-22-5

Acetic acid, [(γ-ω-perfluoro-C8-10-alkyl)thio] derivs., Bu esters

2025

CBI Declassification

82382-12-5

Sodium perfluorohexanesulfonate (PFHxS-Na)

2026

Final Toxicity Value

Note: All PFAS added to the TRI can be accessed via the following link:

https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.epa.gov%2Fsystem%2Ffiles%2Fdocuments%2F2024-01%2Flist-of-pfas-added-to-the-tri-by-the-ndaa.xlsx&wdOrigin=BROWSELINK

Starting January 1, 2026, relevant enterprises must begin tracking the use and handling of PFHxS-Na in accordance with Section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA) and submit their first annual report by July 1, 2027.

 

Further Information

US EPA

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