Update the EU Endocrine Disruptor Assessment List - Modify the evaluation status and outcome of 4 substances-Jul 4,2025

Time: Jul 4, 2025

The European Union's Endocrine Disruptor Assessment List is a registry maintained by the European Chemicals Agency (ECHA), which includes substances that are undergoing assessment for endocrine-disrupting properties. The latest update to this list was on 26 June 2025, and it contains 129 unique substances/entries.

The list comprises substances that have been submitted to the ECHA Endocrine Disruptor Expert Group for discussion. These substances are undergoing an informal hazard assessment to determine whether they possess endocrine-disrupting characteristics. The outcome of the assessment may indicate that a substance does not have endocrine-disrupting properties; however, if the assessment concludes that a substance does have such properties, formal risk management and decision-making processes must be followed to confirm these characteristics before any regulatory actions can be taken based on these properties.

Main updates:

Substance name CAS No. EC No. Status Outcome
Tributyl citrate 77-94-1 201-071-2 Concluded inconclusive
3,5,5-trimethylcyclohex-2-enone 78-59-1 201-126-0 Concluded inconclusive
Methyl salicylate 119-36-8 204-317-7 Concluded inconclusive
Reaction mass of 3-[(diphenoxyphosphoryl)oxy]phenyl triphenyl 1,3-phenylene bis(phosphate) and tetraphenyl 1,3-phenylene bis(phosphate) - 701-337-2 Concluded inconclusive


Since February 2013, any substance deemed to have or potentially have endocrine-disrupting properties has been included in this list.

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