ECHA Opens Public Consultation on Harmonized Classification and Labelling (CLH) Proposals for 3 Substances

In October 2025, the European Chemicals Agency (ECHA) solicited public comments on the harmonized classification and labeling (CLH) proposals for three substances, with a consultation period of 60 days.

Name	EC Number	CAS Number	Hazard classes open for commenting	Start of consultation	Deadline for commenting
flutolanil (ISO); N-[3-(propan-2-yloxy)phenyl]-2-(trifluoromethyl)benzamide; α,α,α-trifluoro-3′-isopropoxy-o-toluanilide	-	66332-96-5	Explosive Flammable solid Self-reactive substance or mixture Pyrophoric solid Self-heating substance or mixture Substance or mixture which in contact with water emits flammable gas Oxidising solid Substance or mixture corrosive to metals Acute toxicity Skin corrosion/irritation Serious eye damage/eye irritation Skin sensitisation Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity — single exposure Specific target organ toxicity — repeated exposure Hazardous to the aquatic environment Hazardous for the ozone layer	06/10/2025	05/12/2025
1-methylimidazole	210-484-7	616-47-7	Reproductive toxicity Acute toxicity – inhalation Acute toxicity - dermal Acute toxicity - oral	20/10/2025	19/12/2025
imidazole hydrobromide	483-310-2	101023-55-6	Reproductive toxicity	20/10/2025	19/12/2025

The CLH process aims to ensure consistency and transparency in hazard information for chemicals across Europe. This procedure involves assessing the hazardous properties of chemical substances, proposing appropriate classifications and labels, collecting public input, and concluding with a final review and recommendations by ECHA's Committee for Risk Assessment (RAC).

Further Information

ECHA