On 4 November 2025, the UK Health and Safety Executive (HSE) proposed adding three reproductive toxic substances to the Authorization List (Annex 14) of the UK Registration, Evaluation, Authorization and Restriction of Chemicals (UK REACH) regulation and initiated a public consultation. This marks the first time the UK has proposed adding substances to the authorization list since its departure from the EU ("Brexit").
|
Material name |
EC number |
CAS Registry Number |
SVHC properties |
Latest Application Date (LAD) |
sunset date |
|
DOTE（2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate） |
239-622-4 |
15571-58-1 |
Reproductive toxicity (Article 57c) |
the date of inclusion in Annex 14 Plus 18, 21 or 24 months |
Latest application date plus 18 months |
|
Reaction mass of DOTE and MOTE |
- |
- |
Reproductive toxicity (Article 57c) |
the date of inclusion in Annex 14 Plus 18, 21 or 24 months |
Latest application date plus 18 months |
|
Tetraethyllead |
201-075-4 |
78-00-2 |
Reproductive toxicity (Article 57c) |
the date of inclusion in Annex 14 Plus 18, 21 or 24 months |
Latest application date plus 18 months |
Second Batch of Potential Regulatory Substances Disclosed
|
Material name |
EC number |
CAS Registry Number |
|
Reaction products of 1,3,4- thiadiazolidine-2,5-dithione, formaldehyde and 4- heptylphenol, branched and linear (RP-HP) [with ≥ 0.1% w/w 4-heptylphenol, branched and linear] |
No single EC number. Representative identifiers include 939-460-0 and 300-298-5. |
No single CAS number. Representative identifiers include 1471311-26-8 and 93925-00-9 |
|
4,4’-bis(dimethylamino)-4”-(methylamino)trityl alcohol [with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)], |
209-218-2 |
561-41-1 |
The feedback period closes on 4 February 2026. Companies operating in the UK must submit localized data on the substances’ current uses in the UK, exposure scenarios, possibilities for exemptions, and feasibility of alternatives.
Further Information
