11 substances were added to the EU Endocrine Disruptor Assessment List-Feb 27,2026

Time: Feb 27, 2026

The European Union's Endocrine Disruptor Assessment List is a registry maintained by the European Chemicals Agency (ECHA), which includes substances that are undergoing assessment for endocrine-disrupting properties. The latest update to this list was on 18 February 2026, and it contains 137 unique substances/entries.

The list comprises substances that have been submitted to the ECHA Endocrine Disruptor Expert Group for discussion. These substances are undergoing an informal hazard assessment to determine whether they possess endocrine-disrupting characteristics. The outcome of the assessment may indicate that a substance does not have endocrine-disrupting properties; however, if the assessment concludes that a substance does have such properties, formal risk management and decision-making processes must be followed to confirm these characteristics before any regulatory actions can be taken based on these properties.

Main updates:

  • 1 substance name revised: Mono- and di-ortho-phthalate esters with at least one of the following: - a linear or branched alkyl moiety with a C4-C6 backbone* with possible substitution by methyl and/or ethyl groups; - a benzyl moiety with methylene possibly substituted by methyl and/or ethyl groups; - a cyclopentyl or cyclohexyl moiety with possible substitution by methyl and/or ethyl groups. [*The backbone is defined as the longest linear carbon chain from the ester function]
  • Assessment status/outcome revised for 4 substances:
    1. 3-phenoxybenzyl-2-(4-ethoxyphenyl)-2-methylpropyl ether;
    2. Oxybenzone;
    3. Geraniol;
    4. 4,4'-isopropylidenedi-2,6-xylol
  • 11 new substances added for assessment:
Substance name CAS No. EC No. Status Outcome
1,2-benzisothiazol-3(2H)-one 2634-33-5 220-120-9 Under development Under development (BPR)
Didecyldimethylammonium chloride 7173-51-5 230-525-2 Under development Under development (BPR)
Quaternary ammonium compounds, benzyl-C12-16-alkyldimethyl, chlorides 68424-85-1 270-325-2 Under development Under development (BPR)
2-phenoxyethanol 122-99-6 204-589-7 Under development Under development (BPR)
6,6'-di-tert-butyl-4,4'-thiodi-m-cresol 96-69-5 202-525-2 Under development Under development (SEV)
Dioctyltin oxide 870-08-6 212-791-1 Under development Under development (other)
perchloric acid and its salts - - Under development Under development (other)
Potassium dicyanoargentate 506-61-6 208-047-0 Under development Under development (SEV)
Triethyl phosphate 78-40-0 201-114-5 Under development Under development (SEV)
Tris(2-ethylhexyl) phosphate 78-42-2 201-116-6 Under development Under development (SEV)
3,5,5-trimethylcyclohex-2-enone 78-59-1 201-126-0 Under development Under development (other)

Since February 2013, any substance deemed to have or potentially have endocrine-disrupting properties has been included in this list.

Disclaimer
1.
CIRS aims to keep the content of this site accurate and up to date. However, CIRS makes no warranties or representations regarding the quality, accuracy, completeness or reliability of information on the site.
2.
In no event shall CIRS assume or have any responsibility or liability for any information on this site or for any claims, damages or losses resulting from their use.
3.
CIRS reserves the right, at our discretion, to change, modify, add to, or remove portions of information on this site at any time without notice.
icon-server
Hot Services
message
in