U.S. Safer Chemical Ingredients List is available

*Green circle – verified low hazard on the basis of robust experimental and modeled data. *Green half-circle – expected low hazard; additional data would further strengthen confidence. *Yellow triangle – functionally necessary but has some hazard-profile gaps. These best-in-class ingredients (e.g., certain preservatives or solvents) are the safest currently available for their specific use, yet their function remains a priority for safer-chemistry innovation. *Grey square – under review for potential removal. Manufacturers have 12 months to submit justification; otherwise the chemical is delisted. By flagging yellow-triangle and grey-square substances, the system not only helps formulators quickly select safer inputs and avoid high-concern chemicals, but also steers the supply chain toward continuous innovation and higher safety standards.