On June 17, 2026, the Ministerial Ordinance Specifying Chemicals Based on the Enforcement Order of the Chemical Substances Control Law, jointly issued by Japan’s Ministry of Health, Labour and Welfare, Ministry of Economy, Trade and Industry, and Ministry of the Environment, officially entered into force.
This revision updates the List of Class I Specified Chemical Substances under Japan’s CSCL, with the adjustments detailed below:
1. Entries 37, 38 and 39 in the original list are renumbered sequentially to Entries 38, 39 and 40 respectively.
2. A new dedicated Entry 37 is added to regulate perfluorohexane-1-sulfonic acid-related compounds. This entry covers a total of 117 controlled chemical substances corresponding to 121 CAS Registry Numbers.

117 Substances (121 CAS numbers) were added to the Japan CSCL-Class I Specified Chemical Substances

On May 19, 2026, Japan’s Ministry of the Environment issued an announcement stating that the Cabinet Office has approved a Cabinet Decision on the Partial Revision Order to the Enforcement Decree of the Chemical Substances Control Law (CSCL).
This revision officially adds Long-Chain Perfluoroalkyl Carboxylic Acids (LC-PFCAs) and their salts, LC-PFCA-related substances, Chlorpyrifos, and Medium-Chain Chlorinated Paraffins (MCCPs) to the list of CSCL Class I Specified Chemical Substances, with supporting regulatory provisions updated accordingly.
The revised ordinance shall officially take effect on November 22, 2026.
For full details: https://www.env.go.jp/press/press_04704.html

4 substances were added to the Japan CSCL-Class I Specified Chemical Substances

Recently, Japan issued an updated announcement, classifying 6 substances as Category I Specified Chemical Substances, with a total of 39 groups of substances now listed.

6 substances were added to the Japan CSCL-Class I Specified Chemical Substances

On January 21, 2026, Japan’s Ministry of Health, Labour and Welfare, Ministry of Economy, Trade and Industry, and Ministry of the Environment jointly released the draft ministerial ordinance for the designation of chemical substances based on the “Order for Enforcement of the Chemical Substances Control Law.” The draft proposes to list 117 chemical substances, including perfluorohexanesulfonic acid (PFHxS) and its related compounds, as “Class I Specified Chemical Substances” under the Chemical Substances Control Law (CSCL), subjecting them to strict regulatory control. The draft is now open for public comments, with the consultation period ending on February 19, 2026. The formal legislation is expected to be promulgated around April 2026 and is scheduled to take effect from June 17, 2026. Relevant enterprises are advised to closely monitor the legislative progress, conduct timely compliance assessments, and adjust production strategies and supply chain arrangements in advance.

117 substances were added to the Japan CSCL-Class I Specified Chemical Substances

11 substances were added to the Japan CSCL-Class I Specified Chemical Substances

197 substances were added to the Japan CSCL-Class I Specified Chemical Substances

2 substances were deleted from the Japan CSCL-Class I Specified Chemical Substances

61 substances were added to the Japan CSCL-Class I Specified Chemical Substances

7 substances were added to the Japan CSCL-Class I Specified Chemical Substances

39 substances were added to the Japan CSCL-Class I Specified Chemical Substances

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