ECHA Opens Public Consultation on Harmonized Classification and Labelling (CLH) Proposals for Two Substances | regulatory trends

On August 25, 2025, the European Chemicals Agency (ECHA) initiated a public consultation on harmonized classification and labelling (CLH) proposals for two substances, with a feedback deadline of October 24, 2025.

Name	EC Number	CAS Number	Hazard classes open for commenting	Start of consultation	Deadline for commenting
3-aminopropyldiethylamine; N,N-diethyl-1,3-diaminopropane	203-236-4	104-78-9	Reproductive toxicity Acute toxicity - dermal Acute toxicity - oral Specific target organ toxicity – repeated exposure Skin sensitisation Endocrine disruptor for human health Endocrine disruptor for the environment	25/08/2025	24/10/2025
3-aminopropyldimethylamine; N,N-dimethyl-1,3-diaminopropane	203-680-9	109-55-7	Reproductive toxicity Acute toxicity - dermal Acute toxicity – oral Specific target organ toxicity – single exposure Specific target organ toxicity – repeated exposure Skin sensitisation Endocrine disruptor for human health Endocrine disruptor for the environment	25/08/2025	24/10/2025

The CLH process aims to ensure consistency and transparency in hazard information for chemicals across Europe. This procedure involves assessing the hazardous properties of chemical substances, proposing appropriate classifications and labels, collecting public input, and concluding with a final review and recommendations by ECHA's Committee for Risk Assessment (RAC).

Further Information

ECHA

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