Recently, the Ministry of Health, Labour and Welfare of Japan announced that, as per the provisions of the Industrial Safety and Health Act (ISHA), 169 chemical substances published on June 26, 2026, have been added to the Japan ISHA-Newly Announced Chemical Substances. These newly added chemicals primarily include substances known to be used in the workplace and potentially impacting worker health.
The update from the Ministry provides detailed information including the names of the chemicals, official gazette numbers, CAS numbers, chemical structural formulas, and classification codes, enabling businesses and research institutions to more accurately identify and manage these substances.

169 substances were added to the Japan ISHA-Newly Announced Chemical Substances

Recently, the Ministry of Health, Labour and Welfare of Japan announced that, as per the provisions of the Industrial Safety and Health Act (ISHA), 171 chemical substances published on March 27, 2026, have been added to the Japan ISHA-Newly Announced Chemical Substances. These newly added chemicals primarily include substances known to be used in the workplace and potentially impacting worker health.
The update from the Ministry provides detailed information including the names of the chemicals, official gazette numbers, CAS numbers, chemical structural formulas, and classification codes, enabling businesses and research institutions to more accurately identify and manage these substances.

171 substances were added to the Japan ISHA-Newly Announced Chemical Substances

On December 26, 2025, the Japanese Ministry of Health, Labour and Welfare announced that, in accordance with the provisions of the Industrial Safety and Health Act (ISHA), 131 chemical substances have been added to the existing list of chemical substances. These newly added chemical substances are primarily those commonly used in the workplace and may affect the health of workers.
The Ministry of Health, Labour and Welfare pointed out that for the newly added chemical substances, companies no longer need to submit a declaration to the Ministry when producing or importing these substances, which helps to simplify the compliance process for businesses. Nevertheless, companies are still required to comply with other safety regulations, including providing Safety Data Sheets (SDS), implementing necessary health and safety measures, and conducting occupational health monitoring.
Furthermore, the Ministry of Health, Labour and Welfare emphasized that for chemical substances not listed on the existing ISHA list, companies still need to conduct assessments and declarations before production or importation, including submitting detailed information on the chemical substances, safety data, potential risks, and intended use, for a more stringent risk assessment and regulation. This ensures that the use of these chemical substances in the workplace does not pose a threat to the health of employees.

167 substances were added to the Japan ISHA-Newly Announced Chemical Substances

149 substances were added to the Japan ISHA-Newly Announced Chemical Substances.

149 substances were added to the Japan ISHA-Newly Announced Chemical Substances

119 substances were added to the Japan ISHA-Newly Announced Chemical Substances.

119 substances were added to the Japan ISHA-Newly Announced Chemical Substances

157 substances were added to the Japan ISHA-Newly Announced Chemical Substances.

157 substances were added to the Japan ISHA-Newly Announced Chemical Substances

131 substances were added to the Japan ISHA-Newly Announced Chemical Substances.

131 substances were added to the Japan ISHA-Newly Announced Chemical Substances

141 substances were added to the Japan ISHA-Newly Announced Chemical Substances.

141 substances were added to the Japan ISHA-Newly Announced Chemical Substances

143 substances were added to the Japan ISHA-Newly Announced Chemical Substances.

Update History