On December 15, 2025, the European Chemicals Agency (ECHA) publicly invited comments on the harmonized classification and labeling (CLH) proposal for four substances. The comment period is 60 days.
|
brodifacoum (ISO); 4-hydroxy-3-(3-(4′-bromo-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)coumarin |
259-980-5 |
56073-10-0 |
Acute toxicity – inhalation |
15/12/2025 |
13/02/2026 |
|
fluoxapiprolin (ISO); 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}-4-piperidinyl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate |
- |
1360819-11-9 |
Explosive |
15/12/2025 |
13/02/2026 |
|
reaction products of phosphoryl trichloride and methyloxirane [1]; tris(2-chloro-1-methylethyl) phosphate [2]; bis(2-chloro-1-methylethyl) 2-chloropropyl phosphate [3]; bis(2-chloropropyl) 2-chloro-1-methylethyl phosphate [4]; tris(2-chloropropyl) phosphate [5]; any individual stereoisomer of the substances listed above and any combination thereof [6] |
- [1] 237-158-7 [2] - [3] - [4] 228-150-4 [5] - [6] |
1244733-77-4 [1] 13674-84-5 [2] 76025-08-6 [3] 76649-15-5 [4] 6145-73-9 [5] - [6] |
Carcinogenicity |
15/12/2025 |
13/02/2026 |
|
Tris[2-chloro-1-(chloromethyl)ethyl] phosphate |
237-159-2 |
13674-87-8 |
Reproductive toxicity |
15/12/2025 |
13/02/2026 |
The CLH process aims to ensure consistency and transparency in hazard information for chemicals across Europe. This procedure involves assessing the hazardous properties of chemical substances, proposing appropriate classifications and labels, collecting public input, and concluding with a final review and recommendations by ECHA's Committee for Risk Assessment (RAC).
Further Information
